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PhD student Safal Khanal and Dr John Phillips (with Drs Phil Turnbull and Ehsan Vaghefi) recently published a paper on a non-invasive MRI method for reliably obtaining quantitative measures of blood perfusion in the human eyes.

Due to the difficulty in measuring blood perfusion in the human eye, the exact pathogenesis of ischemic retinal diseases such as Diabetic Retinopathy (DR) and age-related macular degeneration (AMD) is not yet fully understood, and the treatment options for these conditions continue to be limited. We have successfully implemented a novel, non-invasive MRI method to obtain reliable quantitative measures of blood perfusion in the human retina and choroid. Our study findings have significant clinical implications, particularly for longitudinal studies of ischemia and the investigation of treatments/drug therapies aimed at reducing the progression of ischemic retinal diseases.

This paper is published in the Journal of Magnetic Resonance Imaging.

Read the paper here